Screening of plants used in Danish folk medicine to treat depression and anxiety for affinity to the serotonin transporter and inhibition of MAO-A. Hepatoprotective activity of Apium graveolens and Hygrophila auriculata against paracetamol and thioacetamide intoxication in rats.

^ a b c d e Volatile components of celery and celeriac.The therapeutic applications of celery oil seed extract on the plasticizer di(2-ethylhexyl) phthalate toxicity. 3.3TestesĢ00mg/kg celery oil to rats also given the testicular toxic phthalate (DHEP) was able to exert protective effects when coingested. Lower doses (100-200mg/kg) of water extracts of the aerial parts of celery were not significantly effective, and this anti-ulcer effect against ethanol has been noted elsewhere. In an ulcer test, 300mg/kg of the methanolic and water extracts of celery seeds in a gastric ulcer test (induced by alcohol) was able to inhibit 91% and 95% of the ulceration, respectively a similar potency to the active control omeprazole (94%). The methanolic extract of the seeds has shown protective effects against thioacetamide and paracetamol (assessed by liver enzymes in serum and histological examination). Γ-himachalene (10.3% in portuguese volatiles, 0.3% in italian )īack to top 3Interactions with Organ Systems 3.1LiverĬelery oil (50µl/kg orally) for 6 weeks has shown protective effects in an animal model of DHEP toxicity (a phthalate alongside Bisphenol A that targets PPARα and confers antiandrogenic properties given alongside the celery oil for 6 weeks) was able to attenuate the increase in relative liver weight and lipids as well as serum lipids and liver enzymes. Limonene (35.5-39.4%, some sources note a variability as low as 5.6% ) Other minor phthalide compounds such as p-heptylphenol methyl sedanonate (trace), cis-sedanolide (5.0%) and trans-sedanolide (1.4%) cnidilide. Neophytadiene (34.6–36.7% of the extract in italian sourced volatiles, 0.5-5.2% in Portuguese ) and neocnidilide (36.2–45.2% in Portuguese extracts, 7.6-19.5% in italian ) Ligustilide (also present in Angelica sinensis, and Ligusticum chuanxiong, ) 3-butyltetrahydrophthalide 24% )Ĥ,7-dimethoxy-5-(prop-2-enyl)benzo-1,3-dioxolan or apiole (23% ) Whereas the volatile component of celery (between 0.25% and 1.5-3.0% of celery by weight) tends to contain: The information below may not apply to vegetable consumption if using the seed oil 1.1CompositionĬelery seed oil is comprised of both the oil component (fatty acids) and the volatile component (small molecular weight molecules) the fatty acids in celery seed oil include: The difference between the 'vegetable' or 'stem' (edible portion of celery commonly seen in grocery stores) and the seeds or seed oil (common component of supplement) should be emphazied. The aroma and characteristic taste of celery is thought to be secondary to the sedanenolide component. It has also been reported to be diluted in beverages and drunk with wine to cool a hot temper. Despite the stem being the most commonly ingested portion of the plant as a common vegetable, the seeds of celery appears to have been used for medicinal purposes (Egypt and China) to treat bronchitis, asthma, liver and spleen diseases and with hepatoprotective activity against many hepatotoxins.

The term 'celeriac' refers to a variant of this species known as apium graveolens var. Apium graveolens (of the family Apiaceae) is a vegetable commonly referred to as 'Celery', which has apparently been cultivated for over 3000 years mostly in Egypt.

Celery seed